How to wean your baby off reflux medications

In short... With the guidance of their prescribing doctor.

Note: I’m deliberately avoiding using drug names in this blog because google won’t show you this blog if I do. This information is in relation to the medication classes of H2RA's and PPI's and does not apply to alginate therapies such as G a v i s c o n.

Weaning from medication is a sensitive subject.

I get ALOT of questions about medications in the Facebook group I host for anyone who enrols in a Baby Reflux Lady course, and the answer is always the same: we can’t answer these questions in a group setting.

It pains me to say that, however it’s so true.

The point of this blog, however, is not to say that we cannot help. Quite the opposite, in fact.

To wean your baby off their reflux medications they must be ready to wean off them. And you just understand how these medications work in the first place.

All too often I see parents starting to wean from medications for things to get even worse than ever and they think this means their baby still needs the medications, however, quite the opposite could be the truth.

To understand why this crops up with weaning, we first need to understand how the medications work.

How Reflux Medications Work

Focussing today on PPI medications as the H2RA class are not being prescribed widely at this time.

The medications block these little cells in the stomach, called the Proton Pumps. These cells are the ones responsible for producing the acid component for stomach juices. The dose of the medications will depend on what proportion of these cells get blocked or "inhibited". However, the mere act of blocking the cells does not stop the body from wanting to produce stomach acid to digest food, this is what it is supposed to do.

When we eat, our stomach produces a neurotransmitter called Histamine-2, which acts as a signal to get the stomach to produce stomach acid. When the stomach cannot produce enough acid to digest the food, it increased the amount of histamine produced in an attempt to get more stomach acid in there. 

Eventually the body will reach its highest possible level of histamine production, and this is usually where the "dose" of medications appear to work, or at least baby's body is not longer able to produce stomach acid so any regurgitation that is happening is not damaging their oesophagus.

Weaning off Medications

One of the few true occurrences of our bodies actually over producing stomach acid is when gastric acid suppression (GAS) medication (which is the most common type of medication your little one is on if they have prescription medication for their reflux) is being reduced.

What this means is that as you reduce the dose of GAS meds, your little ones body will truly be in a state where they are over producing stomach acid.


Because the increased levels of histamine-2 become "learned" by your baby's body, they become a "status quo", a set level, so that every time your baby's stomach receives food, it naturally produces this high level of histamine-2 as it knows that this is what it needs to do to get stomach acid produced.

However, when the medications are removed, the high levels of histamine remain, encouraging the stomach to produce high levels of stomach acid. With the proton pumps now actually able to produce stomach acid again, this leaves them responding to the forced high levels of histamine and so they produce far too much stomach acid than what is actually needed to digest the food in the stomach.

Over time, the stomach will relearn the new level of histamine needed to produce the stomach acid needed for the food consumed. However, there is a time lag between the medications being removed and the stomach returning to its natural state of acid production. And the longer a person is taking these medications, the longer it is for their body to find it's normal.

What does this mean?

This means that far too often our babies appear to have reflux driven from the medication wean, when in truth, it is the natural process that their body has to go through to find it's new normal.

And too often this is interpreted as a sign that baby still needs the medications, rather than their bodies been given the time to adjust.

And yet this adjustment period could cause more oesophageal damage by once again, exposing the oesophagus to stomach acid that is not supposed to be there.

So we are stuck between a rock and a hard place...

Or are we?

The truth is that GAS medications do not, and never have, addressed the underlying cause of reflux, because babies do not over produce stomach acid naturally (they do when they are teething and as outlined above).

So what are we to do? We know we don't want our children on these medications long term, and yet no one has a plan to get them off them. Or any of the attempts to wean have made this so much worse than before and you cannot possibly put your child through that distress to get them off medications, especially as the distress could last weeks, and cause more harm to their bodies.

When the underlying cause of your baby's reflux has been addressed, then you should be able to wean off their medications very easily without causing more damage.

How to wean from medications

If your baby is experiencing reflux with a medication wean, then they are having stomach acid coming into their oesophagus. This is not caused by an over production of stomach acid, nor a weak lower oesophageal valve. There is a different cause. And when we find that cause and address it, we stop baby's body from regurgitating anything.

Your baby should be able to keep milk, water and food in their stomach. And if they cannot (reflux) then there is a reason for it. If this is not addressed, then when you try to wean from medications then their body will regurgitate stomach acid into their oesophagus.

However, in the scenario where the cause for their reflux has been addressed and they no longer experience any episodes of regurgitation, then when you wean from the medications, their stomach will over produce acid, however, it should be able to contain it within their tummy, without regurgitating it and so avoiding damaging the oesophagus completely.

Yes they will likely experience some discomfort with bottom irritation from excess stomach acid passing through their gut, however there are other coping strategies we can use to minimise this, and the digestive tract can neutralise most acid, and is designed to be able to cope with small excesses of stomach acid... it's the natural progress of food through the body.

So the answer lies in understanding what is causing your baby's reflux, and addressing this first. Then, when you are confident that they do not suffer from regurgitation at all, get in touch with their doctor and plan the wean off the medication.

If you want to understand what is causing your baby's reflux and how to resolve it so that you can get them off their medications too, the Reflux Free Baby workshop is the starting place. If they have gotten worse with solids, you may also need the Reflux Free Baby Food course that addressed how and why foods make reflux worse for 54% of babies and how to change things so that they are free from their reflux.

If you feel like you are not getting the support you need from your doctor, I can support you in conversations with them and help you plan a medication wean for you to discuss with your doctor to see if it's appropriate for your baby. Given the nature and uniqueness of how every child responds to medications, foods, reflux, weaning etc, I can only provide this support in a 1:1 situation. If you are interested in knowing if I start a group support for medication weaning, please email me to let me know and I'll contact you if this becomes something I create.

Are you beyond ready to help your baby overcome reflux?! 

Download a FREE symptom tracker now to start your journey to conquering reflux for good 👇

Get the tracker >

50% Complete

The best place to start is always to pinpoint the symptoms your baby is experiencing. It's these symptoms which will lead you to the underlying causeaka. the real issue that needs resolving!

Enter your details below to access your FREE symptom tracker: